SUMMARY. Secondary osteoporosis is less common than primary osteoporosis. It may be suspected in patients who present with a fragility fracture despite having no risk factors for osteoporosis. In addition, secondary osteoporosis should be considered if the bone density Z-score is –2.5 or less.
Secondary Fracture Prevention: An International Perspective: Seibel, Markus: the rationale for pursuing a workup to prevent fractures in this patient population. osteoporosis, fragility fracture prevention, orthogeriatrics, fracture registries,
Secondary osteoporosis is loosely defined as low bone mineral density or increased risk of fragility fracture Secondary causes of bone loss are not often considered in patients who are diagnosed as having osteoporosis. In some studies, 20% to 30% of postmenopausal women and more than 50% of men with osteoporosis have a secondary cause. There are numerous causes of secondary bone loss, includ-ing adverse effects of drug therapy, endocrine disorders, In addition, low BMD Z-scores (age-matched comparison) identify individuals requiring further evaluation for secondary causes of osteoporosis. Early diagnosis and quantification of bone loss and fracture risk are important because of the availability of therapies that can slow or even reverse the progression of osteoporosis. primary osteoporosis, and Treat the secondary cause or consider an e-consult with Endocrinology. No Yes N/A Treat the secondary cause and re-check DEXA in 2–3 years, or consider an e-consult with Endocrinology. No No N/A Offer pharmacologic treatment for primary osteoporosis.
Secondary causes of osteoporosis should be corrected or treated if possible. The women should be recommended sufficient inta … The diagnosis of osteoporosis should only be considered in premenopausal women with existing fragility fractures, diseases or treatments known to cause bone loss or fractures. The presence of secondary causes of bone loss may further increase the risk of fracture independently of BMD and may necessitate earlier pharmacologic intervention. Dual-energy X-ray absorptiometry is indicated in the initial workup of secondary causes of osteoporosis.
Secondary causes of bone loss are not often considered in patients who are diagnosed as having osteoporosis. In some studies, 20% to 30% of postmenopausal women and more than 50% of men with osteoporosis have a secondary cause. There are numerous causes of secondary bone loss, including adverse effects of drug therapy, endocrine disorders, eating disorders, immobilization, marrow-related
Secondary osteoporosis is defined as bone loss that results from specific, well-defined clinical disorders. Many times reversible, secondary causes of bone loss are not considered in a patient with low bone mineral density (BMD). Secondary osteoporosis may be Se hela listan på aafp.org CONCLUSIONS: Primary care providers should be further educated on treatable secondary causes of osteoporosis as opposed to an often reflexive response of prescribing a pharmacological antiresportive agent without other consideration.
Secondary osteoporosis: differential diagnosis and workup. There are numerous causes of secondary osteoporosis including endocrine disorders, nutritional deficiencies, and other miscellaneous conditions and medications. It is essential to identify and address these factors to appropriately manage patients with osteoporosis.
One reasonable diagnostic approach is described here.
8 If secondary osteoporosis is suspected, appropriate diagnostic work-up could identify a different management course. For example, if a
In patients with newly diagnosed osteoporosis, suggested laboratory tests to identify secondary causes include serum 25-hydroxyvitamin D, calcium, creatinine, and thyroid-stimulating hormone. A growing understanding of other factors that contribute to the susceptibility of fragility fractures, many of which are not reflected in BMD testing, has expanded the spectrum of patients considered at risk and in need of a workup. Secondary osteoporosis is loosely defined as low bone mineral density or increased risk of fragility fracture
Secondary causes of bone loss are not often considered in patients who are diagnosed as having osteoporosis.
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2016-02-10 · osteoporosis educational site for physicians and patients. For an uncomplicated patient with osteoporosis, a lab workup would be a chemistry panel (electrolytes, bicarbonate, creatinine, albumin, calcium, alkaline phosphatase), CBC, phosphate, TSH and 24-hour urine calcium.
Secondary osteoporosis is not an uncommon condition. There are conflicting data on the prevalence of secondary osteoporosis, being reported in 17–30% and 21–80% of women and men, respectively.
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(lung and throat), coronary artery disease, early menopause, osteoporosis/fractures, and impotency. Secondary outcomes included safety, survival and functional assessment at hospital Is there utility for lab workup in this patient population?
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Aliya A. Khan, David A. Hanley, John P. Bilezikian, Neil Binkley, Jacques P. Brown, Anthony B. Hodsman, Robert G. Josse, David L. Kendler, E. Michael Lewiecki, Paul D
In severe cases, something simple like a sneeze or cough can cause a fracture. There are some things that you can do, however, to strengthen your bones an Osteoporosis is the thinning of bone tissue and loss of bone density over time. Learn about osteoporosis causes, treatments and prevention.